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Phexin®

Phexin®

Phexin® is an antibiotic used to treat infections caused by bacteria, which include bone (osteomyelitis), middle ear, skin, and urinary tract infections (cystitis, pyelonephritis, prostatitis). Phexin® will not work for viral infections like colds, flu and for mycoses.  Show full description

Active ingredients

Other names for this medication

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Phexin® (Cephalexin) 500mg

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Description

Phexin® manufacturer is GSK. The active constituent of Phexin® is Cephalexin, a semisynthetic antibiotic from the drug class first generation Cephalosporins.

Indications:

- upper respiratory tract infections (pharyngitis, otitis media);

- skin and skin structure infections;

- bone infections (osteomyelitis);

- genitourinary infections (cystitis, pyelonephritis, prostatitis);

Phexin® can prevent endocarditis (inflammation of the heart valve) caused by an infection.

MOA (mechanism of action):

Cephalexin works by inhibiting the synthesis of the bacteria’s cell walls. This ruptures the walls and results in the death of bacteria. Cephalexin is found to be active against following microorganisms: aerobes, gram-positive (Staphylococcus aureus (including penicillinase-producing strains), Streptococcus pneumoniae (penicillin-susceptible strains), Streptococcus pyogenes); aerobes, gram-negative (Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella (Branhamella) catarrhalis, Proteus mirabilis).

Dosage

Phexin® capsules should be swallowed whole and taken with a full glass of water.

Treatment course is administered for 7 to 14 days.

Continue to take Phexin® even if you feel well.

Do not stop taking Phexin® suddenly.

For otitis media (middle ear infection):

Adults: The usual dose is 250 mg taken every 6 hours.

Children (ages 1–14 years): 75–100 mg per kg of body weight, taken daily in divided doses.

The doctor may double the dose in case of severe infection.

For skin and skin structure and bone infections:

Adults: 1–4 g per day taken in divided doses. The usual dose is 250 mg taken every 6 hours or 500 mg taken every 12 hours. If you have a severe infection, your doctor may give you a larger dose.

Children (ages 1–14 years): 25–50 mg per kg of body weight, taken daily in 4 divided doses.

The doctor may double this dose for severe cases.

For genitourinary infections and for pharyngitis:

Adults: the usual dose is 250 mg taken every 6 hours. If you have uncomplicated cystitis, you may be given 500 mg every 12 hours.

Children (ages 1–14 years): 25–50 mg per kg of body weight, taken daily in divided doses.

The doctor may double this dose for severe cases.

For endocarditis prevention:

Adults: 2 g taken 30–60 minutes before your procedure.

Children (ages 1–14 years): 50 mg/kg of body weight taken 30–60 minutes before your procedure.

The total child’s dose shouldn’t exceed the adult dosage.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Phexin® to compensate the missed dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effects

The most common side effects associated with Phexin® are:

  • antibiotic-associated diarrhea
  • dizziness
  • fatigue
  • headache
  • joint pain
  • vaginal itching or discharge

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Phexin® if you are allergic to Cephalexin or to other Cephalosporins (e.g., Cefaclor, Raniclor, Cefadroxil, Duricef).

Do not take Phexin® if you are allergic to any ingredient comprised in Phexin®.

Do not take Phexin® if you have a history of severe allergic reactions associated with using antibiotics.

Do not take Phexin® if you have a history of clostridium difficileassociated diarrhea (CDAD).

Do not take Phexin® if you suffer from an inherited metabolic disorder called porphyria.

Do not take Phexin® if you experience blood clotting problems and take anticoagulants (e.g., Warfarin), as taking Phexin® may decrease the ability of blood to clot.

Do not take Phexin® if you take Metformin (for diabetes type 2 treatment), Probenecid (for gout and hyperuricemia treatment).

Do not take Phexin® if you experience problems with stomach or bowel (inflammation), kidney or liver, or if you have poor nutrition.

Patients with diabetes mellitus who test their urine for glucose should use glucose tests based on enzymatic glucose oxidase reactions while using Phexin®.

Do not take Phexin® if you are pregnant, plan to have a baby or are breastfeeding.

If you are taking vitamin supplements, do not take them for 2 hours before or after taking Phexin®.

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Frequently asked questions

Q: What is Phexin® used for?

A: Phexin® is an antibiotic used to treat infections caused by bacteria, which include bone (osteomyelitis), middle ear, skin, and urinary tract infections (cystitis, pyelonephritis, prostatitis).

Q: Is Phexin® safe?

A: Phexin® is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q: Can I take Phexin® for a cold?

A: Phexin® will not work for viral infections like colds, flu and for mycoses.

Q: Does Phexin® treat sexually transmitted diseases (STDs)?

A: Phexin® is not approved to treat STDs. It may be used against staph infections, but is not very effective against bacterial vaginosis.

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