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Fasigyn®

Fasigyn®

Fasigyn® is an antibiotic used to treat a variety of bacterial infections of the gums, the pelvic cavity, and the tummy (abdomen). It is also prescribed before gynecological surgery and surgery on the intestines to prevent infection from developing. Fasigyn® is an alternative medication for people who are allergic to penicillin. Fasigyn® does not work for viral infections and mycoses (infections caused by fungi).  Show full description

Active ingredients

Other names for this medication

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Description

Fasigyn® manufacturer is Pfizer.

Fasigyn® tablets contain active ingredient is Tinidazole, a 5-nitroimidazole anti-parasitic agent, which belongs to a drug class Amebicides, Antimalarials and gynecological Antiinfectives.

Indications:

- genitourinary tract infections in both women and men caused by trichomonas vaginalis, including vaginitis, giardiasis, trichomoniasis, amebiasis, endometritis or abscess in the ovaries/fallopian tubes;

- prevention of anaerobic infections following gynecological or abdominal surgery;

- bacterial infections in the abdomen (peritonitis); abscess in the pelvic cavity;

- bacterial infection of the blood (septicaemia);

- bacterial skin and soft tissue infections;

- bacterial infections of the respiratory tract, such as pneumonia or lung abscesses;

- painful inflammation and ulcers of the gums (ulcerative gingivitis);

- parasitic gut infection caused by the protozoa Giardia lamblia (giardiasis);

- amoebic infection of the liver or intestine;

- part of a treatment to fight Helicobacter pylori (infection associated with stomach and duodenal ulcers).

MOA (mechanism of action):

Tinidazole is used to treat infections caused by bacteria and other microorganisms called protozoa. Tinidazole enters bacterial and protozoal cells and interferes with their DNA. It destroys the DNA and does not allow the bacteria and protozoa to form new genetic material. This ultimately results in death of microorganisms, which gets rid of the infection.

Dosage

Fasigyn® tablets should be taken with plenty of water with or after meal.

Swallow Fasigyn® tablets whole, do not chew or crush.

Fasigyn® is not recommended for use in children less than 12 years.

For urogenital Trichomoniasis: The recommended dose is 4 tablets (2 g) given as a single dose.

For amoebic involvement of the liver (a liver infection): the recommended dose is 3 to 4 tablets (1,5 to 2 g) once a day for 3 to 6 days.

For the infection associated with stomach ulcers: the recommended dose is 1 tablet (500 mg) taken twice a day.

For most bacterial infections: the recommended dose is 4 tablets (2 g) on the first day then 2 tablets (1 g) once a day or 1 tablet (500 mg) twice a day. The usual length of treatment is 5 to 6 days.

For bacterial vaginitis (a vaginal infection) and acute ulcerative gingivitis (a gum infection): the recommended dose is 4 tablets (2 g) given as a single dose. For vaginitis you may be given 4 tablets (2 g) on two consecutive days.

For protozoal infections (intestinal amoebiasis): the recommended dose is 4 tablets (2 g) once a day for 2 to 3 days.

Prevention of postoperative infections in adults (over 12 years): the recommended oral dose of 2 g approximately 12 hours before surgery.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Fasigyn® to compensate the missed dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effects

The most common side effects associated with Fasigyn® are:

  • allergic reactions
  • nausea (feeling sick)
  • vomiting
  • loss of appetite
  • diarrhea
  • stomach pain or cramps
  • headache
  • vertigo
  • skin rash or itching

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Fasigyn® if you are allergic to Tinidazole, to any antibiotic from the class Amebicides.

Do not take Fasigyn® if you are allergic to any of the other ingredients comprised in Fasigyn®.

Do not take Fasigyn® if you have a history of severe allergic reactions associated with using antibiotics.

Do not take Fasigyn® you have a blood disorder or a history of blood disorders.

Do not take Fasigyn® if you have any disease of the brain, spinal cord or nerves.

Do not take Fasigyn® you have central nervous system (CNS) disease, including epilepsy.

Do not take Fasigyn® you are in the first 13 weeks of pregnancy, planning to have a baby, or you are breastfeeding.

Do not drive or operate machinery if you feel dizzy or numb after taking Fasigyn®.

Do not consume alcohol while you are taking Fasigyn® and for 3 days afterwards. Alcohol may cause an upset stomach, vomiting, stomach cramps, headaches, sweating, and flushing (redness of the face).

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Frequently asked questions

Q: Is Fasigyn® good for flu, cough?

A: Fasigyn® will not fight viral infections such as colds or flu.

Q: Can women take Fasigyn® during pregnancy?

A: Do not take Fasigyn® you are in the first 13 weeks of pregnancy, planning to have a baby, or you are breastfeeding. Fasigyn® passes into breast milk and may harm baby.

Q: Is Fasigyn® safe?

A: Yes, it is. Fasigyn® is relatively safe medication, if taken as recommended. In case of any side effects, consult your doctor.

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