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Erythromycin

 Erythromycin

Erythromycin is a antibacterial medication that is commonly used to treat infections caused by various bacteria (e.g., pharyngitis, laryngitis, sinusitis, tonsillitis, tracheitis, acute and chronic bronchitis, pneumonia, otitis, blepharitis, syphilis, Gonorrhea etc). Erythromycin may be suggested as alternative medication in case patient has hypersensitivity to penicillin.  Show full description

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Description

Erythromycin is a macrolide antibiotic, also known as a protein synthesis inhibitor.

Indications:

- upper respiratory tract infections (tonsillitis, pharyngitis, laryngitis, sinusitis);

- lower respiratory tract infections (tracheitis, bronchitis, pneumonia, bronchiectasis, Legionnaire's disease);

- skin and other soft tissue infections (acne);

- ear infections (otitis media and otitis externa, mastoiditis);

- mouth infections;

- eye infections (blepharitis);

- gastrointestinal infections (e.g. gallbladder or intestinal infections);

- sexually transmitted diseases (syphilis, Gonorrhea).

Erythromycin is used for preventing infections when you:

- are going to have or have recently had dental or surgical procedures;

- have suffered from burns;

- have had rheumatic fever;

- are allergic to penicillin and have heart disease.

Erythromycin may be used to improve delayed stomach emptying. Erythromycin is not used to treat infection due to viruses like cold and flu and yeast infections.

MOA (mechanism of action):

Erythromycin can be used to treat bacterial infections of the skin and upper respiratory tract due to Streptococcus, Staphylococcus, Haemophilus and Corynebacterium genera. Erythromycin slows or stops the growth and multiplication of bacteria. It blocks the synthesis of essential proteins, which are required by bacteria to carry out vital functions.

Dosage

Swallow the Erythromycin pills whole, without food, at least 1 half hour up to 2 hrs before eating food. Do not crush or chew the pill.

For adults, elderly:

Recommended dose is one 250 mg tablet 4 times per day with a maximum dose of 4 grams per 24 hours.

Erythromycin 500 mg tablet should be taken twice a day. Total doses over 1 g per day should be divided into 4 doses per 24 hours.

For children (2 to 8 years):

Recommended dose is 30-50 mg/Kg/day (milligrams per Kilogram per 24 hours), but should not to exceed 4 g per day.

For infants and babies up to 2 years:

Erythromycin tablets are not appropriate for infants and babies up to 2 years.

Therefore use of Erythromycin granules for oral suspension is recommended.

Treatment course in average lasts 10-14 days. However it may vary due to a condition. Consult your doctor for before you start taking Erythromycin pills.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Erythromycin to compensate the missed dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effects

The most common side effects associated with Erythromycin are:

  • allergic reactions
  • nausea
  • vomiting
  • abdominal pain
  • diarrhea
  • anorexia
  • hepatic dysfunction
  • abnormal liver function

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Erythromycin pills if you are allergic to Erythromycin, other macrolide antibiotics (Azithromycin, Clarithromycin, and Roxithromycin).

Do not take Erythromycin pills if you are allergic to any of the other ingredients comprised in Erythromycin pills.

Do not take Erythromycin if you have a history of severe allergic reactions associated with using antibiotics.

Do not take Erythromycin if you are taking antihistamines such as terfenadine, mizolastine, astemizole; anti-psychotic drugs (for mental illness) such as pimozide; dihydroergotamine or ergotamine (to treat migraines); cisapride (for stomach problems); cilostazol (for cramp-like pains in the legs when walking).

Do not take Erythromycin if you have liver disease or are taking medications affecting your liver.

Do not take Erythromycin if you suffer from myasthenia gravis (muscle weakness, difficulty chewing and swallowing and slurred speech).

Consult your doctor before taking Erythromycin if you are pregnant or breastfeeding.

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Frequently asked questions

Q: What is Erythromycin?

A: Erythromycin is a antibacterial medication that is commonly used to treat infections caused by various bacteria (e.g., pharyngitis, laryngitis, sinusitis, tonsillitis, tracheitis, acute and chronic bronchitis, pneumonia, otitis, blepharitis, syphilis, Gonorrhea etc). Erythromycin may be suggested as alternative medication in case patient has hypersensitivity to penicillin.

Q: Does Erythromycin cause gas, weight gain, and drowsiness?

A: Erythromycin may cause gas, weight gain and drowsiness.

Q: Does Erythromycin cause weight gain, tiredness, or headache?

A: Erythromycin may cause weight gain, tiredness, and headache. These effects may vary with the individual taking the medicine.

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