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Deriva® MS Gel

Deriva® MS Gel

Deriva® MS Gel is a topical anti-acne medication. This gel contains retinoid and possesses strong comedolytic and peeling properties. Deriva® MS Gel is formulated for adults and teenagers over 12 years of age.  Show full description

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Other names for this medication

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Deriva® MS Gel (Adapalene) 0.1%, 15 g

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Description

Deriva® MS Gel is manufactured by Glenmark. It is used to treat mild to moderate acne on the face, chest, and back. The active substance of Deriva® MS Gel is Adapalene, a third-generation retinoid and derivative of vitamin A. Adapalene is considered as a first-line therapy for comedonal and inflammatory acne.

Acne (also known as acne vulgaris) is a common skin disorder caused by an overgrowth of P. acnes (Propionibacterium acnes) bacteria, that live and grow in the clogged pores. Pores can get clogged when containing too much skin sebum and excess dead epithelial cells. The symptoms of acne are pimples, whiteheads, non-inflamed comedones, blackheads, and possible scarring of the lesions.

MOA (mechanism of action):

Adapalene acts as comedolytic and anti-inflammatory agent. It penetrates the clogged pores, where modulates cells differentiation and keratinization, thereby decreasing the amount of dead skin cells residue and inhibiting the formation of comedogenic content. With the lack of pore-clogging content in pores, P. acnes no longer have a positive environment to proliferate in.

Dosage

Deriva® MS Gel is for external use only. Do not apply to your eyes, mouth, inside of the nose, private parts, and any other mucosal surface.

Deriva® MS Gel is normally applied 1 time daily at bedtime, usually for 3 months. In case your acne has not improved after 2-3 weeks of treatment, discontinue the Deriva® MS Gel use and seek medical advice.

How to use Deriva® MS Gel:

1. Wash your hands and the affected areas with mild soap or cleanser, pat dry.

2. Apply a thin layer of the gel to the affected areas with your finger tips.

3. Gently rub until the gel is mostly absorbed.

4. Wash your hands after the gel application.

Precautions

Do not use Deriva® MS Gel longer than 6 months.

Do not apply Deriva® MS Gel in combination with harsh skin products, medicated soaps and shampoos, products with drying effect on the skin, peeling agents, or products containing alcohol.

Patients should use sunscreens (min. SPF 15) and protective clothing while using Deriva® MS Gel.

Do not apply Deriva® MS Gel to the irritated, itchy, cracked or burnt skin (sunburns and windburns included).

Do not apply Deriva® MS Gel to the open wounds or cuts.

Do not cover the Deriva® MS Gel application site with occlusive bandages or other covering.

Do not use Deriva® MS Gel in combination with harsh skin products, medicated soaps and shampoos, products with drying effect on the skin, peeling agents, products containing alcohol, spices or lime.

Do not apply skin moisturizers or makeup to the skin being treated with Deriva® MS Gel 1 hour before and after the gel application.

Due to the flammable nature of Deriva® MS Gel, avoid smoking or being near an open flame while you are applying Deriva® MS Gel and immediately after you have used it.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not apply a double dose.

Overdose

Do not exceed the doctor's recommended dose. If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at a room temperature from 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away the tube after the expiration date. Keep away from children.

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Side effects

The most common side effects associated with the use of Deriva® MS Gel are:

  • dry skin
  • itchy skin
  • burning or stinging sensation
  • redness
  • skin rash
  • contact dermatitis
  • redness, itching or swelling of the eyelids

Side effects occurrence does not only depend on the medication you are using, but also on your overall health and other factors.

Contraindications

Do not apply Deriva® MS Gel if you are allergic to Adapalene.

Do not apply Deriva® MS Gel if you have a history of severe allergic reactions associated with the use of retinoids or vitamin A.

Do not apply Deriva® MS Gel if you are allergic to any of the other ingredients comprised in Deriva® MS Gel.

Do not use Deriva® MS Gel if you are taking any photosensitizers (porfimer, verteporfin), acne medications (salicylic acid) or antifungals (sodium thiosulfate).

Do not use Deriva® MS Gel if you have eczema, seborrheic dermatitis or a skin abrasion.

Avoid sunlight (UV) exposure while using Deriva® MS Gel, as it may potentiate the side effects of Adapalene.

Do not apply Deriva® MS Gel if you have sunburn, windburn or skin irritation with redness, peeling or itching.

Do not use Deriva® MS Gel in children under 12 years of age.

Deriva® MS Gel is strictly prohibited in women who are pregnant, plan to have a baby or are breastfeeding.

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Frequently asked questions

Q: What Deriva® MS Gel is used for?

A: Deriva® MS Gel is used to treat mild to moderate comedonal and inflammatory acne.

Q: Is Deriva® MS Gel safe for teenagers?

A: Deriva® MS Gel is safe for children over 12 years of age, as far as used for prescribed condition and at prescribed doses.

Q: Can Deriva® MS Gel be used in pregnant women?

A: No. Deriva® MS Gel is strictly prohibited for women who are pregnant, planning to have a baby or breastfeeding.

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